Understand what a pentosan polysulfate sodium is all about


The pentosan polysulfate sodium (PPS) treats discomfort/ pain from a specific bladder disorder known as interstitial cystitis. It may function by forming a layer on the bladder wall and shielding it from irritating/ harmful substances in the urine. It is a weak blood thinner and may boost the risk of bleeding/ bruising such as bleeding from the gums/nose. Pentosan Polysulfate Sodium is a man made drug manufactured from the wood chips of beech trees in Europe. The main characteristics of the activity of PPS are its tissue recreating and anti-inflammatory properties and also mild anti-thrombotic activity. This medication prescribed is used to ease bladder discomfort and pain. Pentosan polysulfate sodium can be used in children at least 16 years old and adults.

Know how to use Pentason Polysulfate Sodium

Pentosan Polysulfate comes as a capsule to be taken by mouth, it is mostly taken with water 3x a day, it must be 1 hour before or 2 hours after meals. You need to carefully read and follow the directions on the prescribed label. Also, ask your pharmacist or doctor to describe any part you do not comprehend. You have to absorb pentosanpolysulfate as instructed, do not take less or more usually than what is prescribed by your doctor. You shouldn’t take it for a longer period unless it is ordered by the doctor.

Before taking pentosan polysulfate, know what precautions you should follow:

  • You need to inform your pharmacist and your doctor if you are allergic to danaparoid, pentosan polysulfate, heparin, or any other medications.
  • Tell your pharmacist and doctor what nonprescription and prescription medications, nutritional supplements, vitamins, and herbal products you are consuming. Your doctor may have to alter the doses of your medications or check you carefully for any side effects.
  • Let your doctor know if you have or have ever had hemophilia, intestinal blockage, aneurysm, ulcers, spleen or liver disease, or low platelet count.
  • Also, tell your doctor or dentist that you are taking pentosan polysulfate once you are having surgery including dental surgery.
  • You need to be aware that pentosan polysulfate may cause increased bleeding since it has a blood-thinning effect.

PPS has been inspected in safety studies and toxicology across various species of animals to humans for over 50 years. It has been infused in the bladder, taken orally, and injected.

You must have a written list of the nonprescription and prescribed over-the-counter medicines you are consuming. Also, any products such as minerals, vitamins, or any other dietary supplements. You have to carry this list each time you go to a doctor or if you are admitted to a hospital. It is also vital information to keep with you in case of any emergencies or injury.

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